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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES3
All Species:
0.91
Human Site:
S167
Identified Species:
2
UniProt:
Q5TGS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGS1
NP_001019769.1
186
19968
S167
A
S
S
R
C
A
E
S
P
G
L
G
L
R
V
Chimpanzee
Pan troglodytes
XP_001162588
239
25232
A171
L
G
S
Q
A
G
E
A
A
K
V
F
G
G
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546749
200
21060
A182
S
V
P
G
P
Q
P
A
P
R
Q
C
T
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61657
175
19275
A157
D
V
V
A
P
H
P
A
S
N
C
Q
A
E
S
Rat
Rattus norvegicus
Q04667
175
19118
A157
G
I
L
A
P
P
P
A
S
N
C
Q
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511924
287
29320
G194
P
G
G
A
A
A
P
G
G
G
G
G
G
G
G
Chicken
Gallus gallus
O57337
290
31053
T210
G
F
Q
L
V
P
A
T
D
G
Q
F
A
F
L
Frog
Xenopus laevis
Q8AVU4
267
28644
P212
Y
G
G
F
Q
L
V
P
A
S
D
G
Q
F
A
Zebra Danio
Brachydanio rerio
Q9I9L0
324
34311
A221
E
A
P
Q
R
G
A
A
L
F
S
H
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
I215
Q
M
G
G
L
Q
L
I
P
S
R
L
P
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175739
383
41428
L306
P
T
I
S
P
A
Q
L
Q
P
S
T
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
N.A.
67
N.A.
65.5
63.9
N.A.
25.7
24.1
25.8
22.5
N.A.
20.9
N.A.
N.A.
21.9
Protein Similarity:
100
39.7
N.A.
70
N.A.
70.4
72
N.A.
35.8
36.2
35.9
33.3
N.A.
29.6
N.A.
N.A.
31.3
P-Site Identity:
100
13.3
N.A.
6.6
N.A.
0
0
N.A.
20
6.6
6.6
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
N.A.
20
N.A.
6.6
6.6
N.A.
20
20
6.6
20
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
28
19
28
19
46
19
0
0
0
28
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
19
10
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% D
% Glu:
10
0
0
0
0
0
19
0
0
0
0
0
0
28
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
10
0
19
0
19
10
% F
% Gly:
19
28
28
19
0
19
0
10
10
28
10
28
19
19
19
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
10
10
10
10
10
10
10
0
10
10
10
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% N
% Pro:
19
0
19
0
37
19
37
10
28
10
0
0
10
0
0
% P
% Gln:
10
0
10
19
10
19
10
0
10
0
19
19
10
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
10
10
0
0
10
0
% R
% Ser:
10
10
19
10
0
0
0
10
19
19
19
0
10
10
37
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
10
10
0
0
% T
% Val:
0
19
10
0
10
0
10
0
0
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _